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Case Reports

Osmotic Demyelination Syndrome Presenting with Parkinsonism

Authors:

N. T. Weerasinghe ,

National Hospital Kandy, LK
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L. M. Safeek,

National Hospital Kandy, LK
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P. J. P. Peiris,

National Hospital Kandy, LK
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S. Azher

National Hospital Kandy, LK
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Abstract

Osmotic demyelination syndrome (ODS) is a condition which occurs due to rapid osmotic changes which result in myelinolysis of the nervous system. Uncommonly the myelinolysis could involve areas beyond the pons resulting in extrapontine myelinolysis (EPM). We report a 70-year-old gentleman who presented with a 2-week history of reduced interaction and altered behavior with parkinsonism following oral correction of severe hyponatraemia. Magnetic resonance imaging (MRI) of the brain revealed hyperintensities in the T2-weighted FLAIR images involving the pontine region with no involvement of basal ganglia. This case illustrates the significance of adhering to recommended protocols when correcting hyponatraemia and the importance of timing brain imaging in ODS.
How to Cite: Weerasinghe, N.T., Safeek, L.M., Peiris, P.J.P. and Azher, S., 2022. Osmotic Demyelination Syndrome Presenting with Parkinsonism. Sri Lanka Journal of Medicine, 31(1), pp.126–129. DOI: http://doi.org/10.4038/sljm.v31i1.325
Published on 15 Aug 2022.
Peer Reviewed

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