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A rare case of a diffuse intrinsic pontine glioma presenting as pathological laughter and apparent hyperactivity in a child

Authors:

S. R. Perera ,

Base Hospital Nikaweratiya, LK
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A. S. Rajapakshe

Base Hospital Nikaweratiya, LK
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Abstract

Introduction: Diffuse intrinsic pontine gliomas generally present with cranial nerve palsies with cerebellar and pyramidal-tract involvement. The pons has generally not been regarded as a structure that mediates complex affective behaviour. However pathological laughter has been reported with pontine pathology in various forms. 

 

Case Presentation: We present a case of pontine glioma presenting as pathological laughter and apparent hyperactivity in a previously healthy 11-year-old boy.

 

Discussion: Literature states that pontine gliomas are the subgroup of brainstem gliomas with the worst prognosis. This patient remained with deficits in motor functions and coordination despite intense treatment with radiotherapy.
How to Cite: Perera, S.R. and Rajapakshe, A.S., 2021. A rare case of a diffuse intrinsic pontine glioma presenting as pathological laughter and apparent hyperactivity in a child. Sri Lanka Journal of Medicine, 30(2), pp.101–103. DOI: http://doi.org/10.4038/sljm.v30i2.259
Published on 30 Dec 2021.
Peer Reviewed

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