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Case of a young girl with marked bone marrow plasmacytosis

Authors:

V. C. Panditha Gunwardena ,

National Hospital Kandy, LK
About V. C.
Department of Haematology
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A. D. Siribaddana,

National Hospital Kandy, LK
About A. D.
Respiratory Unit
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A. J. Hilmi,

National Hospital Kandy, LK
About A. J.
Oncology and radiotherapy unit
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R. M. P. Rathnayake,

National Hospital Kandy, LK
About R. M. P.
Department of Pathology
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G. C. M. Weerasooriya

National Hospital Kandy, LK
About G. C. M.
Haematology Unit
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Abstract

Marked plasmacytosis in the bone marrow is a rare finding in young people. If present it is secondary to an underlying disease condition. Castleman disease is a rare form of lymphoproliferative disorder. Due to its rarity, it is not frequently considered in the differential diagnosis of lymphadenopathy. As in any other lymphoproliferative disorder Castleman disease can also be associated with various immune mediated cytopenia. This case report is on a teenager with persistent lymphadenopathy of whom the presence of marked bone marrow plasmacytosis led to the diagnosis of plasma cell type Castleman disease which went into complete remission with single agent vincristine and radiotherapy with subsequent severe immune thrombocytopenia during follow up.
How to Cite: Panditha Gunwardena, V.C., Siribaddana, A.D., Hilmi, A.J., Rathnayake, R.M.P. and Weerasooriya, G.C.M., 2021. Case of a young girl with marked bone marrow plasmacytosis. Sri Lanka Journal of Medicine, 30(1), pp.117–121. DOI: http://doi.org/10.4038/sljm.v30i1.280
Published on 01 Jul 2021.
Peer Reviewed

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