Case Reports
A case of thrombotic microangiopathy and acute demyelinating central nervous system lesions as the first manifestation of systemic lupus erythematosus
Authors:
K. D. Ellepola ,
National Hospital, Kandy, LK
R. A. Higgoda,
National Hospital, Kandy, LK
I. K. Jayasinghe,
National Hospital, Kandy, LK
D. R. Chamara,
National Hospital, Kandy, LK
B. G. Premaratne,
National Hospital, Kandy, LK
W. Dissanayake
National Hospital, Kandy, LK
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with a relapsing and remitting course and multi- organ involvement which can present with a wide range of neuropsychiatric manifestations. Acute disseminating encephalomyelitis (ADEM) is an autoimmune demyelinating disorder of the central nervous system (CNS). Thrombotic thrombocytopenic purpura (TTP) is a medical emergency which manifests with microangiopathic haemolytic anaemia (MAHA), thrombocytopenia and neurological abnormalities and is known to be a rare association of SLE. We report a case of a 14 year old female who presented with fever and altered consciousness, subsequently diagnosed to have SLE with thrombotic microangiopathy and acute demyelinating CNS lesions in an ADEM-distribution
How to Cite:
Ellepola, K.D., Higgoda, R.A., Jayasinghe, I.K., Chamara, D.R., Premaratne, B.G. and Dissanayake, W., 2021. A case of thrombotic microangiopathy and acute demyelinating central nervous system lesions as the first manifestation of systemic lupus erythematosus. Sri Lanka Journal of Medicine, 30(1), pp.109–112. DOI: http://doi.org/10.4038/sljm.v30i1.247
Published on
01 Jul 2021.
Peer Reviewed
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